Fedratinib

https://www.macmillan.org.uk › ... › treatments-and-drugs › fedratinib
Fedratinib Inrebic is a cancer drug It is used to treat a type of blood cancer called myelofibrosis MF

https://www.drugs.com › fedratinib.html
Fedratinib is used for certain types of myelofibrosis MF in adults relieving night sweats itching pain feeling full after eating and spleen volume Myelofibrosis is a rare type of bone marrow

https://www.mayoclinic.org › drugs-supplements › ...
Fedratinib is used to treat intermediate 2 or high risk myelofibrosis including primary or secondary post polycythemia vera and post essential thrombocythemia myelofibrosis

https://ashpublications.org › bloodadvances › article
Fedratinib s JAK2 selectivity and kinome profile make it an appealing agent for alternative indications such as myelodysplastic myeloproliferative neoplasms and maintenance after bone

https://packageinserts.bms.com › pi › pi_inrebic.pdf
INREBIC fedratinib is available as 100 mg equivalent to 117 3 mg of fedratinib dihydrochloride monohydrate hard gelatin capsules for oral administration Each capsule contains inactive

https://www.nice.org.uk › guidance
This guidance updates and replaces NICE technology appraisal guidance 756 on fedratinib for treating disease related splenomegaly or symptoms in myelofibrosis which was

https://www.medicines.org.uk › emc › product
Inrebic 100 mg hard capsules Active Ingredient fedratinib dihydrochloride monohydrate

https://www.ema.europa.eu › en › documents › product...
Thus fedratinib can be taken with or without food since no clinically meaningful effect on the pharmacokinetics of fedratinib was observed with food Administration with a high fat meal may

https://www.ema.europa.eu › en › medicines › human › EPAR › inrebic
The active substance in Inrebic fedratinib works by blocking an enzyme known as JAK2 which is involved in the production and growth of blood cells In myelofibrosis there is too much JAK