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https://pmc.ncbi.nlm.nih.gov › articles
In this review we highlight the emerging insights that link mTOR to various processes related to aging such as nutrient sensing maintenance of proteostasis autophagy mitochondrial

https://www.sciencedirect.com › science › article › pii
AMPK is an important kinase regulating energy homeostasis and also a key protein involved in a variety of signal transduction pathways It plays a vit

https://onlinelibrary.wiley.com › doi › epdf
In this study we verified that miR 708 expression is decreased in senescent cells and aged tissues and revealed that miR 708 overexpression can alleviate cellular senescence and aging

https://biologyinsights.com › ampk-and-mtor-the...
AMPK promotes energy conservation during low energy states while mTOR drives growth when nutrients are abundant Understanding how these pathways interact provides

https://www.mdpi.com
AMP activated protein kinase AMPK and mammalian target of rapamycin mTOR are nutrient sensing pathways regulating metabolism AMPK promotes energy

https://www.aginganddisease.org › EN
Exercise mediated ATP depletion activates AMPK while suppressing mTORC1 thereby synchronously inducing autophagy initiation ULK1 phosphorylation and lysosomal biogenesis

https://www.gethealthspan.com › research › article › ampk-mtor-cycling
Importantly AMPK activation not only suppresses mTORC1 a nutrient sensing pathway associated with aging and autophagy inhibition but may also spare or support

https://www.frontiersin.org › journals › aging › articles › full
We highlight the complex crosstalk of mTORC1 with the formation of stress granules SGs a stress dependent non membranous cellular compartment and we discuss

https://europepmc.org › article › MED
These findings not only demonstrate the potential role of miR 708 in aging regulation but also expand the signaling network connecting AMPK and mTORC1